--- Julia Thompson <[EMAIL PROTECTED]> wrote:
> Matt Grimaldi wrote:
> > Alberto Monteiro wrote:
> > >
> > > I once listened from a nutty UFO and psychic
> believer
> > > that water from high up in the mountains was
> more healthy than water from below, because it had
> less Deuterium and Deuterium would accelerate aging.
> > >
> > > Sounds nutty, but - as I said before - might be
> > > true. Mountain people _seem_ to have longer
> lifes than groundhogs
> > >
> > 
> > Not if they fall off a cliff...  :-)
> > 
> > I would guess that their lifestyle, which by
> necessity
> > includes more physical labor, less fast food, etc.
> > contributes a lot more to their longevity than a
> lack of deuterium.
> 
> One question:  What's the infant mortality rate
> among the mountain people in
> question, as opposed to the population they're being
> compared to?  If the
> weaker people die in infancy, the average lifespan
> of the survivors will likely be longer.

Can't back all of this up at the moment, but
off-the-cuff: 

-mountain population tends to be less dense than river
delta population, so infectious diseases ought to be
less prevalent (high density -> higher rate of
infection being passed)

-tropical diseases more prevalent at delta altitude
(more bugs and bacteria and viruses) than at high
altitude

-I recall seeing Andean glacier water had a high
mineral content, and there is some evidence (posted
previously) that this has health benefits;  delta
river water has a lot of sediment but I don't know
about the dissolved mineral content (guessing less),
and of course many more bacteria/protozoans -- some of
them pathogens

-one study did suggest a slightly lower longevity for
women at very high altitudes (it didn't pop up in my
limited search, however)

-A Russian study found "The influence of natural and
man-made factors on the longevity of people in
Tadzhikistan was studied. The studies indicated that
high-altitude hypoxia had an adverse effect on their
longevity while premountain and low-mountain areas of
the republic were the most beneficial."  [I'm going to
guess that this population has not adapted yet to
altitude -- see last 2 studies below.]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10975187&dopt=Abstract

-another notes a higher rate of death from emphysema
in Colorado despite the younger average age of
residents:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7103248&dopt=Abstract
"...Emphysema deaths at higher altitudes in Colorado
(greater than or equal to 7,000 ft) occur at a younger
age...after a shorter duration of illness, and more
commonly from cor pulmonale than at lower altitudes
(less than or equal to 4,500 ft) where pneumonia is
more common as the immediate cause of death. The
mechanism by which high altitude residence interacts
unfavorably with survival is not known but may stem
from augmented pulmonary hypertension caused by the
hypoxia of lung disease added to the hypoxia of high
altitude."

This older (1982) study I think is suspect:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7094209&dopt=Abstract
"...For most comparisons a deficit in cancer mortality
in high altitude counties was observed. The largest
differences between the low and high altitude groups
were found for cancers of the tongue and mouth,
esophagus, larynx, lung and melanoma. Some limitations
of ecologic studies are discussed."  [As this is a US
study, and all but melanoma are tobacco-related
cancers, I suspect self-selection is one of the
limitations: smokers are more likely to have COPD, get
short-of-breath, and move to lower altitudes before
they die.  Melanomas are of course more common with
higher UV exposure in the mountains.]

-here is are studies on infant mortality that mention
both Himalayan and Andean infants, and add to Julia's
supposition that generations of "survival of the
fittest" has produced hardier sub-populations:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7943187&dopt=Abstract
"...Data derived from reproductive histories revealed
that neonatal mortality accounted for 70-80% of total
infant mortality in Ladakh [India]. Compared to other
high-altitude studies, small newborn size in Ladakh
was associated with much higher mortality risks;
mortality risk rose dramatically with birthweights
below the mean (2,764 grams), which characterized 50%
of all newborns. It is argued that newborns in Ladakh
are subject to strong directional selective forces
that favor higher birthweights that incur lower risks
of neonatal mortality, while Andean infants are
subject to relatively mild selection pressure at both
ends of the birthweight distribution. Given the
overall small size at birth of Ladakhi newborns and
the poor survival outcomes of newborns below the mean,
it is suggested that this population is less well
adapted in a biological sense to the stresses inherent
in this high-altitude environment than are Andean
populations, perhaps due to the relatively recent
colonization of the area and the substantial genetic
admixture that has occurred in the past."

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8317562&dopt=Abstract
...In comparison with literature observations, the
altitude-associated difference in birth weight was
smallest in Tibetans, intermediate in South America,
and greatest in North America. These data support the
hypothesis that Tibetans are protected from
altitude-associated intrauterine growth retardation
and suggest that selection for optimization of birth
weight at high altitude has occurred in Tibetans."

Debbi
Mile High Maru  :)

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