*biointelligence 8th feb 2010*
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*Dinucleotide Properties Genome Browser: DiProGB*
Whole genomes have now been sequenced from a long time. The basic aim of
computational genome analysis is to understand the information encoded in
the genomes. Apart from the nucleotide sequence, the related physical
properties also play an important role.
* DiProGB* is a standalone computer program
written in VC++.It is an easy to use new genome browser that encodes the
primary nucleotide sequence by thermodynamical and geometrical dinucleotide
properties. The nucleotide sequence is thus converted into a sequence graph.
This visualization, supported by different graph manipulation options,
facilitates genome analyses, because the human brain can process visual
information better than textual information. Also, DiProGB can identify
genomic regions where certain physical properties are more conserved than
the nucleotide sequence itself.DiProGB adds a new dimension to the common
genome analysis approaches by taking into account the physical properties of
DNA and RNA.
In DiProGB all annotated features such as genes,
exons, introns or repeat regions and the corresponding qualifiers such as
gene name, product and function can be separately addressed and specifically
colored. All or parts of the annotated information can be displayed for
either a single strand or for both strands together. Overlapping features
are visualized by stacked bars in the so-called feature graph below the
sequence graph.
*More about DiProGB can be read from here:*
*http://diprogb.fli-leibniz.de/introduction.php*
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*Regards,
Team Biointelligence
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*Biointelligence*
*Getting started with biosciences*
*Website: www.biointelligence.in*
*Email: [email protected]
Tel: +91-731-425-7930*
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