Hi Leo, Martin,

it looks like this is related to an issue with the remotes package: 
https://github.com/r-lib/remotes/issues/296 
<https://github.com/r-lib/remotes/issues/296>. It gets the installation order 
wrong, and tries to install source packages before binaries. This can be a 
problem with GenomeInfoDbData (which I think doesn’t have a binary, and which 
it looks like Leo is installing manually). The TxDb package also doesn’t seem 
to be available as a binary package, and currently the source package for 
tibble is newer than the Windows binary. 

According to the issue above, it should have been fixed in remotes v2.1.1 
(https://github.com/r-lib/remotes/commit/88f302fe53864e4f27fc7b3897718fea9a8b1fa9
 
<https://github.com/r-lib/remotes/commit/88f302fe53864e4f27fc7b3897718fea9a8b1fa9>).
 To try things out, I set up a minimal package with the only dependency being 
TxDb.Hsapiens.UCSC.hg19.knownGene (https://github.com/csoneson/testpkg 
<https://github.com/csoneson/testpkg>), and checked it with GitHub Actions on 
macOS and Windows. It fails in both cases, since it’s trying to install 
TxDb.Hsapiens.UCSC.hg19.knownGene first (e.g. 
https://github.com/csoneson/testpkg/runs/619407291?check_suite_focus=true#step:7:533
 
<https://github.com/csoneson/testpkg/runs/619407291?check_suite_focus=true#step:7:533>).
 If I depend instead on GenomicFeatures, everything builds fine (here we have a 
binary). It is using remotes v2.1.1 though, so perhaps this needs to be 
investigated further.

Charlotte

> On 25 Apr 2020, at 22:20, Martin Morgan <mtmorgan.b...@gmail.com> wrote:
> 
> tibble is not a direct dependency of TxDb*.
> 
>> db = available.packages(repos = BiocManager::repositories())
>> deps = tools::package_dependencies("TxDb.Hsapiens.UCSC.hg19.knownGene", db)
>> deps
> $TxDb.Hsapiens.UCSC.hg19.knownGene
> [1] "GenomicFeatures" "AnnotationDbi"
> 
> but it is an indirect dependency
> 
>> deps = tools::package_dependencies("TxDb.Hsapiens.UCSC.hg19.knownGene", db, 
>> recursive=TRUE)
>> "tibble" %in% unlist(deps)
> [1] TRUE
> 
> I did
> 
>  deps1 = tools::package_dependencies("TxDb.Hsapiens.UCSC.hg19.knownGene", db, 
> recursive=TRUE)
> 
>  deps2 = tools::package_dependencies("tibble", db, recursive=TRUE, 
> reverse=TRUE)
> 
>  intersect(unlist(deps1), unlist(deps2))
>  ## [1] "GenomicFeatures" "biomaRt"         "BiocFileCache"   "dbplyr"
>  ## [5] "dplyr"
> 
> I believe R checks for immediate dependencies, found all for TxDb* and 
> GenomicFeatures available, and didn’t check further. I speculate that you 
> removed tibble, or installed one of the packages in the above list, without 
> satisfying the dependencies for that package. Or perhaps what the message is 
> really trying to say is that it failed to load tibble (because it was 
> installed in a previous version of the R toolchain?)
> 
> It would be interesting to debug this further on your system, to understand 
> the problem for other users.
> 
> Martin
> 
> On 4/25/20, 2:48 PM, "Bioc-devel on behalf of Leonardo Collado Torres" 
> <bioc-devel-boun...@r-project.org on behalf of lcollado...@gmail.com> wrote:
> 
>    Hi Bioc-devel,
> 
>    I think that there's a potential issue with either GenomicFeatures,
>    TxDb.Hsapiens.UCSC.hg19.knownGene or an upstream package.
> 
> 
>    On a fresh R 4.0 Windows installation with BioC 3.11, I get the
>    following error message when installing
>    TxDb.Hsapiens.UCSC.hg19.knownGene as shown at
>    
> https://github.com/leekgroup/derfinderPlot/runs/618370463?check_suite_focus=true#step:13:1225.
> 
> 
>    2020-04-25T18:32:26.0765748Z * installing *source* package
>    'TxDb.Hsapiens.UCSC.hg19.knownGene' ...
>    2020-04-25T18:32:26.0769789Z ** using staged installation
>    2020-04-25T18:32:26.1001400Z ** R
>    2020-04-25T18:32:26.1044734Z ** inst
>    2020-04-25T18:32:26.2061605Z ** byte-compile and prepare package for
>    lazy loading
>    2020-04-25T18:32:30.7296724Z ##[error]Error: package or namespace load
>    failed for 'GenomicFeatures' in loadNamespace(i, c(lib.loc,
>    .libPaths()), versionCheck = vI[[i]]):
>    2020-04-25T18:32:30.7305615Z ERROR: lazy loading failed for package
>    'TxDb.Hsapiens.UCSC.hg19.knownGene'
>    2020-04-25T18:32:30.7306686Z * removing
>    'D:/a/_temp/Library/TxDb.Hsapiens.UCSC.hg19.knownGene'
>    2020-04-25T18:32:30.7307196Z  there is no package called 'tibble'
>    2020-04-25T18:32:30.7310561Z ##[error]Error: package 'GenomicFeatures'
>    could not be loaded
>    2020-04-25T18:32:30.7311805Z Execution halted
> 
>    From looking at the bioc-devel landing pages for both GenomicFeatures
>    and TxDb.Hsapiens.UCSC.hg19.knownGene, I see that tibble is not listed
>    as a dependency for either package.
> 
>    Best,
>    Leo
> 
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