Hello Bioconductor developers,

As you've probably noticed already, we're building BioC 3.11 on Mac again:

  https://bioconductor.org/checkResults/3.11/bioc-LATEST/

The build target now is High Sierra (used to be El Capitan), like for the official Mac built of R 4.0.0 alpha (available here https://mac.r-project.org/) and for the Mac binary packages available on CRAN. This means that the binaries we produce are only compatible with High Sierra or higher, as long as you're using the official Mac built of R 4.0.0.

IMPORTANT: CRAN and Bioconductor binary packages for Mac are NOT meant to be used with an R 4.0.0 installed from source (they're likely to crash your session, typically at load time).

Using BiocManager::install() with the official Mac built of R 4.0.0 will pick up binary packages from CRAN and Bioconductor 3.11. It will fall back on source packages only when the binaries are not available.

Please let us know if you run into any problem with this.

Cheers,
H.

--
Hervé Pagès

Program in Computational Biology
Division of Public Health Sciences
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N, M1-B514
P.O. Box 19024
Seattle, WA 98109-1024

E-mail: hpa...@fredhutch.org
Phone:  (206) 667-5791
Fax:    (206) 667-1319

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