Thanks for the note Karl, and sorry for the break. For others, the change in DESeq2::lfcShrink is that now type="apeglm" is the default instead of type="normal".
For the past two releases, users have been getting a message when they run with the default argument that type="normal" performs worse the other two shrinkage options available. best, Mike _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel