Hi,
in a lot of the bioinformatics analysis I have to carry out, I end up needing
to take an arbitrary number of GRanges objects and flatten them before
generating a matrix of all elements that overlap. This is useful for, say,
comparing replicates in a ChIP-seq experiment, or caracterizing the types of
interactions in a HiC or ChIA-PET experiment. As such, I've written quite a few
utility functions around that concept, for example to generate Venn plots of
the intersections, querying specific intersections, or plotting heatmaps of
correlation.
My question is two-fold: are there already existing packages that already
incorporate some of that core functionality, and if not, would repackaging
those functions as a package be of interest to the Bioconductor community at
large?
Thank you for your time,
-Eric Fournier
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