Dear list, I would like to introduce the package bacon that has been added to bioconductor just before the release of version 3.3.
bacon can be used to estimate and control for bias and inflation often present in epigenome- and transcriptome-wide association studies(EWAS/TWAS). The idea behind bacon is to estimate the empirical null distribution from the data (using Bayesian statistics) and use the empirical null i.s.o. a theoretical null for inference. Bacon supports bias- and inflation-controlled fixed-effect meta-analysis that can be executed in parallel. A manuscript is available from biorxiv ( http://biorxiv.org/content/early/2016/05/27/055772). Kind regards, Maarten van Iterson [[alternative HTML version deleted]] _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel
