Memory usage is a common bottleneck. For people interested in profiling their memory usage I want to recommend the lineprof package by Hadley Wickham which I have had great success with so far. There is some details in his 'Advanced R programming' at http://adv-r.had.co.nz/memory.html I see this package as a real game changer.
I have written an example debugging session on a real use case (minfi::preprocessRaw) at http://www.hansenlab.org/rstats/2014/01/30/lineprof/ where I end up having to workaround using new() for Biobase classes (an eSet derived class in minfi) Best, Kasper [[alternative HTML version deleted]] _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel