Dear list,
I'm sharing with you an R library that we have lunched in Bioconductor a
couple of month ago. This package allows you to perform ANOVA decomposition
and PCA analysis (APCA) or ANOVA-Simultaneous Component Analysis (ASCA) in
addition with PLS analysis over the Residual/Coefficients Matrices instead
of PCA.
This library (lmdme) provides a flexible framework for ANOVA decomposition
through linear models of multivariate designed experiments such gene
expression experiment with several experimental factors or clinical
information on subjects. It allows to perform Principal Component and/or
Partial Least Squares Analysis on residuals or coefficient matrices.
The paper will be available soon in Journal of Statistical Software. You
can download the library by means of:
source("http://bioconductor.org/biocLite.R";)
biocLite("lmdme")
It has been successfully applied in microarray quality control and could be
applied in any observed matrix subjected to a experimental design.
Hope you find it useful
Cristobal Fresno
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