Dear bioc-devel, the dist2 function in genefilter defined as:
dist2 <- function (x, fun = function(a, b) mean(abs(a - b), na.rm = TRUE), diagonal = 0) {
if (!(is.numeric(diagonal) && (length(diagonal) == 1L))) stop("'diagonal' must be a numeric scalar.") res = matrix(diagonal, ncol = ncol(x), nrow = ncol(x)) colnames(res) = rownames(res) = colnames(x) if (ncol(x) >= 2) { for (j in 2:ncol(x)) for (i in 1:(j - 1)) res[i, j] = res[j, i] = fun(x[, i], x[, j]) } return(res) } could have it's default function vectorized as: res <- apply(x, 2, function(i) colMeans(abs(x - i), na.rm=TRUE)) to improve performance for example in the ArrayQualityMetrics package. Best. James. _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel