Hi all,

I'm currently experimenting with using quip (https://github.com/dcjones/quip#readme) to save disk space when storing FASTQ and BAM files. One thing that would be nice is to read quip-compressed FASTQ or BAM files directly into R. Obviously direct support for reading quip compression would be ideal, but in the short term, quip supports decompression to standard output, so if I could have R read FASTQ or BAM data from an open file handle, I could pipe the decompressed output to R's FASTQ or BAM reader functions. Does anyone know if this is possible?

-Ryan Thompson

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