Hi Xiaowei,

Thank you for reaching out. To clarify your statement, the mutateMembers() 
operation allows you to add or remove a list of members from the UserList. The 
amount of members in your userlist isn't capped at 500,000, the amount of 
members you can add/remove at a time (not including removeAll) is capped at 
500,000. Now to answer your questions:

Yes, you can do this. You add members by creating your memberList then calling 
the mutateMembers ADD operation.
This won't impact the campaign running. However, just be advised that it can 
take 6 to 12 hours to populate the UserList as explained here.
You can see more information about operation counts here. Each member you add 
will be 1 operation.

Regards,
Mitchell
Google Ads API Team
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